ZNF223

Across TCGA cell cohorts, ZNF223 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,863 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF223-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Autophagy, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with ZNF223 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF223-to-partner and partner-to-ZNF223 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ZNF223-low versus ZNF223-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF223→partner) and Y-score (partner→ZNF223) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.134	+1.246	<.001	.001	3	16
STOMACH	Autophagy →	+0.072	+1.412	.001	<.001	3	15
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.125	+1.433	<.001	<.001	3	15
STOMACH	Process utilizing autophagic mechanism →	+0.072	+1.412	.001	<.001	3	15
STOMACH	Regulation of myoblast fusion →	+0.127	+1.472	<.001	<.001	3	14
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.132	+1.246	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,863 associations by consensus.

Negative regulation of myoblast fusion by ZNF223 expression — STOMACH

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