ZNF223

Across TCGA cell cohorts, ZNF223 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF223-associated genes across cancer lineages are TECTB, TBATA, and ASB17. Each is linked with ZNF223 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF223-to-partner and partner-to-ZNF223 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TECTB grouped by ZNF223-low versus ZNF223-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF223→partner) and Y-score (partner→ZNF223) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TECTB →	+0.028	+3.794	<.001	.001	3	1
CNS	TBATA →	+0.023	+6.357	<.001	<.001	3	1
OVARY	ASB17 →	+0.014	+4.222	<.001	.006	3	1
OVARY	KLHL40 →	+0.007	+4.865	.001	<.001	3	1
BLOOD_Leukemia	ATP1B4 →	+0.079	+3.944	.002	.006	3	1
BLOOD_Leukemia	C20orf173 →	+0.063	+4.133	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

TECTB by ZNF223 expression — BLOOD_Lymphoma

Explore this box plot interactively →