ZNF222

Across TCGA patient cohorts, ZNF222 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,242 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF222-associated proteins across cancer lineages are IRGQ, ANP32E, and XRCC1. Each is linked with ZNF222 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF222-to-partner and partner-to-ZNF222 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF222 versus IRGQ in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF222→partner) and Y-score (partner→ZNF222) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IRGQ →	+0.237	+0.391	<.001	<.001	3	6
HNSC	ANP32E →	+0.421	+0.531	<.001	.002	3	5
GBM	XRCC1 →	+0.381	+0.489	<.001	<.001	3	5
CCRCC	NSUN4 →	-0.303	-0.338	<.001	.008	3	5
HNSC	PPIF →	-0.543	-0.648	<.001	.004	3	5
GBM	SAE1 →	+0.432	+0.436	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,242 associations by consensus.

ZNF222 vs IRGQ — GBM

Explore this scatter interactively →