ZNF222

Across TCGA cell cohorts, ZNF222 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,603 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF222-associated GO terms across cancer lineages are Golgi vesicle transport, COPII-coated vesicle budding, and Vesicle coating. Each is linked with ZNF222 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF222-to-partner and partner-to-ZNF222 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by ZNF222-low versus ZNF222-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF222→partner) and Y-score (partner→ZNF222) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Golgi vesicle transport →	+0.053	+0.585	<.001	<.001	3	9
BONE	COPII-coated vesicle budding →	+0.096	+0.707	.001	<.001	3	9
SOFT_TISSUE	Vesicle coating →	+0.087	+0.859	<.001	<.001	2	9
LUNG_NSCLC_LUSC	Response to type I interferon →	+0.097	+0.765	.001	<.001	3	8
BLOOD_Lymphoma	Internal protein amino acid acetylation →	+0.074	+1.364	<.001	<.001	3	8
URINARY_TRACT	Positive regulation of fibrinolysis →	-1.393	-1.308	.002	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,603 associations by consensus.

Golgi vesicle transport by ZNF222 expression — SKIN

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