ZNF22

Across TCGA cell cohorts, ZNF22 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,694 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF22-associated GO terms across cancer lineages are Mitotic cell cycle phase transition, Regulation of chromosome segregation, and Positive regulation of gluconeogenesis. Each is linked with ZNF22 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF22-to-partner and partner-to-ZNF22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic cell cycle phase transition grouped by ZNF22-low versus ZNF22-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF22→partner) and Y-score (partner→ZNF22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Mitotic cell cycle phase transition →	+0.096	+2.501	<.001	<.001	3	10
SOFT_TISSUE	Regulation of chromosome segregation →	+0.106	+2.801	<.001	<.001	3	9
BREAST	Positive regulation of gluconeogenesis →	+0.062	+1.587	.002	<.001	3	9
CNS	Fatty acid beta-oxidation →	-0.077	-0.988	<.001	.002	3	9
BLOOD_Leukemia	Regulation of G1/S transition of mitotic cell cycle →	+0.050	+0.892	<.001	<.001	3	8
SOFT_TISSUE	Regulation of sister chromatid segregation →	+0.105	+2.804	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,694 associations by consensus.

Mitotic cell cycle phase transition by ZNF22 expression — SOFT_TISSUE

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