ZNF219

Across TCGA patient cohorts, ZNF219 protein abundance is significantly associated with the RNA expression of many other genes, with 14,489 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF219-associated genes across cancer lineages are ACIN1, CCNB1IP1, and APEX1. Each is linked with ZNF219 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF219-to-partner and partner-to-ZNF219 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF219 versus ACIN1 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF219→partner) and Y-score (partner→ZNF219) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ACIN1 →	+0.446	+0.424	<.001	<.001	3	4
LSCC	CCNB1IP1 →	+0.740	+0.601	<.001	<.001	3	4
UCEC	APEX1 →	+0.772	+0.358	<.001	<.001	3	4
LSCC	CHD8 →	+0.428	+0.433	<.001	<.001	3	4
UCEC	AKAP8L →	+0.640	+0.362	.002	<.001	3	4
LSCC	CHD6 →	+0.503	+0.495	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,489 associations by consensus.

ZNF219 vs ACIN1 — BRCA

Explore this scatter interactively →