ZNF219

Across TCGA patient cohorts, ZNF219 mutation is significantly associated with the RNA expression of many other genes, with 1,734 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF219-associated genes across cancer lineages are MIR4510, RNU6-128P, and IGHD1-26. Each is linked with ZNF219 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF219-to-partner and partner-to-ZNF219 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4510 grouped by ZNF219-low versus ZNF219-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF219→partner) and Y-score (partner→ZNF219) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR4510 →	+0.196	+4.342	<.001	.007	3	2
COAD	RNU6-128P →	+0.484	+4.418	.001	.008	3	2
COAD	IGHD1-26 →	+1.335	+3.910	<.001	.006	3	2
COAD	BMI1P1 →	+0.038	+4.537	.002	.006	3	2
COAD	ABHD15-AS1 →	+0.305	+4.769	.006	.001	3	2
LUAD	UBE2Q2P10 →	+0.125	+4.890	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,734 associations by consensus.

MIR4510 by ZNF219 expression — CESC

Explore this box plot interactively →