ZNF215

Across TCGA patient cohorts, ZNF215 mutation is significantly associated with the RNA expression of many other genes, with 3,881 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF215-associated genes across cancer lineages are TUBAP4, RNU6-1316P, and BCAM. Each is linked with ZNF215 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF215-to-partner and partner-to-ZNF215 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TUBAP4 grouped by ZNF215-low versus ZNF215-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF215→partner) and Y-score (partner→ZNF215) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TUBAP4 →	+0.056	+1.656	<.001	.009	3	3
BRCA	RNU6-1316P →	+0.570	+4.325	.008	.007	3	3
UCEC	BCAM →	-1.196	-2.300	<.001	.001	3	3
LGG	OR10G6 →	+0.059	+4.846	<.001	.006	3	3
LGG	CD24P2 →	+0.331	+4.398	<.001	.006	3	3
UCEC	CHEK1 →	+0.677	+2.246	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,881 associations by consensus.

TUBAP4 by ZNF215 expression — SKCM

Explore this box plot interactively →