ZNF215

Across TCGA cell cohorts, ZNF215 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,943 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF215-associated GO terms across cancer lineages are Positive regulation of translation, Establishment of protein localization to organelle, and Ribosomal subunit export from nucleus. Each is linked with ZNF215 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF215-to-partner and partner-to-ZNF215 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of translation grouped by ZNF215-low versus ZNF215-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF215→partner) and Y-score (partner→ZNF215) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of translation →	+0.066	+1.130	.006	.008	2	9
BLOOD_Lymphoma	Establishment of protein localization to organelle →	+0.040	+1.483	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Ribosomal subunit export from nucleus →	+0.089	+1.505	<.001	<.001	3	7
PANCREAS	Maturation of SSU-rRNA →	+0.091	+0.808	<.001	.005	3	7
OVARY	Microtubule nucleation →	+0.095	+1.526	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Ribosome localization →	+0.089	+1.505	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,943 associations by consensus.

Positive regulation of translation by ZNF215 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →