ZNF215

Across TCGA cell cohorts, ZNF215 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF215-associated genes across cancer lineages are OR2M2, BMP10, and OR10A5. Each is linked with ZNF215 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF215-to-partner and partner-to-ZNF215 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2M2 grouped by ZNF215-low versus ZNF215-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF215→partner) and Y-score (partner→ZNF215) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR2M2 →	+0.046	+5.781	<.001	.001	3	1
LARGE_INTESTINE	BMP10 →	+0.021	+3.297	<.001	.002	3	1
LARGE_INTESTINE	OR10A5 →	+0.057	+2.994	<.001	.006	3	1
LARGE_INTESTINE	RSC1A1 →	+0.793	+3.782	.007	.002	3	1
SKIN	OR1L3 →	+0.019	+5.415	<.001	.004	3	1
LUNG_NSCLC_LUAD	PRAMEF2 →	+0.008	+3.734	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR2M2 by ZNF215 expression — BREAST

Explore this box plot interactively →