ZNF214

Across TCGA patient cohorts, ZNF214 mutation is significantly associated with the RNA expression of many other genes, with 4,648 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF214-associated genes across cancer lineages are BCCIP, SUPV3L1, and GOT1. Each is linked with ZNF214 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF214-to-partner and partner-to-ZNF214 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCCIP grouped by ZNF214-low versus ZNF214-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF214→partner) and Y-score (partner→ZNF214) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	BCCIP →	+0.524	+2.597	.005	.005	3	3
UCEC	SUPV3L1 →	+0.335	+2.765	.002	<.001	3	3
UCEC	GOT1 →	+0.350	+1.841	.003	.001	3	3
SKCM	RAC3 →	+0.988	+3.331	.003	.005	3	3
SKCM	MRPS16 →	+0.411	+3.613	.003	.001	3	3
LIHC	RNA5SP339 →	+0.201	+5.008	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,648 associations by consensus.

BCCIP by ZNF214 expression — SKCM

Explore this box plot interactively →