ZNF214

Across TCGA cell cohorts, ZNF214 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,692 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZNF214-associated GO terms across cancer lineages are Macroautophagy, Process utilizing autophagic mechanism, and Autophagy. Each is linked with ZNF214 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF214-to-partner and partner-to-ZNF214 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by ZNF214-low versus ZNF214-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF214→partner) and Y-score (partner→ZNF214) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Macroautophagy →	+0.050	+0.673	<.001	.001	3	14
KIDNEY	Process utilizing autophagic mechanism →	+0.048	+0.498	.002	.005	2	12
KIDNEY	Autophagy →	+0.048	+0.498	.002	.005	2	12
SKIN	Regulation of myoblast fusion →	+0.089	+1.024	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Regulation of protein K48-linked ubiquitination →	+0.105	+0.743	<.001	<.001	3	9
LUNG_SCLC	Protein localization to vacuole →	+0.066	+1.131	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,692 associations by consensus.

Macroautophagy by ZNF214 expression — LUNG_NSCLC_LUAD

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