ZNF214

Across TCGA cell cohorts, ZNF214 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF214-associated genes across cancer lineages are MS4A10, PRAMEF27, and PPY. Each is linked with ZNF214 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF214-to-partner and partner-to-ZNF214 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A10 grouped by ZNF214-low versus ZNF214-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF214→partner) and Y-score (partner→ZNF214) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	MS4A10 →	+0.499	+3.544	<.001	.009	3	2
LARGE_INTESTINE	PRAMEF27 →	+0.003	+4.022	<.001	.006	3	1
LUNG_NSCLC_LUAD	PPY →	+0.049	+3.734	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR52B4 →	+0.011	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MS4A10 by ZNF214 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →