ZNF207

Across TCGA patient cohorts, ZNF207 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF207-associated genes across cancer lineages are Rad50, 4E-BP1, and eIF4E. Each is linked with ZNF207 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF207-to-partner and partner-to-ZNF207 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rad50 grouped by ZNF207-low versus ZNF207-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF207→partner) and Y-score (partner→ZNF207) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rad50 →	-0.235	-1.700	.022	.044	3	2
UCEC	4E-BP1 →	+0.233	+2.999	.042	.035	3	2
UCEC	eIF4E →	+0.186	+3.000	.037	.036	2	2
UCEC	MEK1 →	+0.439	+2.222	.004	.011	3	1
UCEC	PCNA →	+0.186	+2.999	.042	.035	3	1
UCEC	PDCD4 →	-0.447	-3.312	.025	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Rad50 by ZNF207 expression — UCEC

Explore this box plot interactively →