ZNF207

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF207 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF207-associated genes across cancer lineages are IP6K3, KRT6C, and LY6H. Each is linked with ZNF207 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF207-to-partner and partner-to-ZNF207 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IP6K3 grouped by ZNF207-low versus ZNF207-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF207→partner) and Y-score (partner→ZNF207) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaIP6K3 →+0.023+4.234.003.00731
BLOOD_LeukemiaKRT6C →+0.026+4.037<.001.00431
BLOOD_LeukemiaLY6H →+1.017+3.855.008.00731
BLOOD_LeukemiaTCEAL2 →+0.588+3.769.007.00831
BLOOD_LeukemiaIGFL1 →+0.090+3.769<.001.00831
BLOOD_LeukemiaC1orf146 →+0.032+3.769.002.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

IP6K3 by ZNF207 expression — BLOOD_Leukemia

Box plot of IP6K3 in ZNF207-low vs ZNF207-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration