ZNF202

Across TCGA patient cohorts, ZNF202 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF202-associated genes across cancer lineages are IGFBP2, PDK1_pS241, and Shc_pY317. Each is linked with ZNF202 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF202-to-partner and partner-to-ZNF202 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGFBP2 grouped by ZNF202-low versus ZNF202-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF202→partner) and Y-score (partner→ZNF202) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGFBP2 →	-0.601	-1.362	.008	.037	3	2
UCEC	PDK1_pS241 →	+0.174	+2.700	.003	.006	3	2
UCEC	Shc_pY317 →	-0.131	-1.584	.014	.034	3	2
UCEC	Chk2_pT68 →	-0.156	-2.575	.017	.010	3	2
UCEC	C-Raf →	+0.125	+2.222	.013	.010	3	2
UCEC	EGFR_pY1068 →	-0.208	-2.000	.018	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

IGFBP2 by ZNF202 expression — UCEC

Explore this box plot interactively →