ZNF20

Across TCGA patient cohorts, ZNF20 mutation is significantly associated with the RNA expression of many other genes, with 2,242 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF20-associated genes across cancer lineages are SNX3P1Y, HARS2, and CNOT6. Each is linked with ZNF20 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF20-to-partner and partner-to-ZNF20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNX3P1Y grouped by ZNF20-low versus ZNF20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF20→partner) and Y-score (partner→ZNF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNX3P1Y →	+0.070	+3.954	<.001	.006	3	2
UCEC	HARS2 →	+0.390	+2.394	<.001	.002	3	2
UCEC	CNOT6 →	+0.387	+2.413	.006	<.001	3	2
UCEC	SRSF4 →	+0.375	+2.392	.001	<.001	3	2
UCEC	KIF1C →	+0.454	+2.413	<.001	<.001	3	2
UCEC	SRRM1 →	+0.438	+2.403	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,242 associations by consensus.

SNX3P1Y by ZNF20 expression — UCEC

Explore this box plot interactively →