ZNF20

Across TCGA patient cohorts, ZNF20 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF20-associated genes across cancer lineages are ASNS, PR, and eEF2. Each is linked with ZNF20 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF20-to-partner and partner-to-ZNF20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ZNF20-low versus ZNF20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF20→partner) and Y-score (partner→ZNF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.629	+3.700	<.001	.001	3	2
COAD	PR →	+0.250	+2.820	.024	.035	3	2
UCEC	eEF2 →	+0.313	+2.999	.034	.035	3	1
UCEC	eIF4G →	+0.366	+2.321	.004	.033	3	1
UCEC	FASN →	+0.443	+2.459	.006	.019	3	1
UCEC	JNK_pT183_Y185 →	-0.198	-3.459	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

ASNS by ZNF20 expression — UCEC

Explore this box plot interactively →