ZNF20

Across TCGA cell cohorts, ZNF20 mutation is significantly associated with the RNA expression of many other genes, with 541 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF20-associated genes across cancer lineages are SEC14L3, GCAT, and ANKRD54. Each is linked with ZNF20 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF20-to-partner and partner-to-ZNF20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEC14L3 grouped by ZNF20-low versus ZNF20-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF20→partner) and Y-score (partner→ZNF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SEC14L3 →	+0.022	+2.087	<.001	.002	3	1
LARGE_INTESTINE	GCAT →	+1.250	+3.459	<.001	.001	3	1
LARGE_INTESTINE	ANKRD54 →	+0.465	+2.714	.002	.002	3	1
LARGE_INTESTINE	EIF3L →	+0.487	+3.067	.002	.009	3	1
LARGE_INTESTINE	HSCB →	+0.560	+3.169	.001	.009	3	1
LARGE_INTESTINE	CBY1 →	+0.582	+3.459	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 541 associations by consensus.

SEC14L3 by ZNF20 expression — LARGE_INTESTINE

Explore this box plot interactively →