ZNF189

Across TCGA cell cohorts, ZNF189 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,507 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF189-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Regulation of heterochromatin organization, and Protein sumoylation. Each is linked with ZNF189 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZNF189-to-partner and partner-to-ZNF189 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by ZNF189-low versus ZNF189-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF189→partner) and Y-score (partner→ZNF189) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of organelle assembly →	+0.066	+0.922	<.001	<.001	3	12
LUNG_SCLC	Regulation of heterochromatin organization →	+0.126	+0.596	<.001	<.001	3	12
LUNG_SCLC	Protein sumoylation →	+0.091	+0.766	<.001	<.001	3	12
BLOOD_Leukemia	Regulation of organelle assembly →	+0.036	+0.609	<.001	<.001	3	12
STOMACH	Regulation of autophagosome assembly →	+0.063	+0.580	.009	.009	3	12
UPPER_AERODIGESTIVE_TRACT	Response to aluminum ion →	+0.132	+0.677	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,507 associations by consensus.

Positive regulation of organelle assembly by ZNF189 expression — STOMACH

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