ZNF185

Across TCGA cell cohorts, ZNF185 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,718 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF185-associated GO terms across cancer lineages are Protein activation cascade, Positive regulation of exosomal secretion, and Membrane biogenesis. Each is linked with ZNF185 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZNF185-to-partner and partner-to-ZNF185 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein activation cascade grouped by ZNF185-low versus ZNF185-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF185→partner) and Y-score (partner→ZNF185) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein activation cascade →	+0.279	+1.715	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of exosomal secretion →	+0.105	+1.441	<.001	<.001	3	11
OVARY	Membrane biogenesis →	+0.093	+2.020	<.001	<.001	3	11
OVARY	Membrane assembly →	+0.089	+1.940	<.001	<.001	3	11
LARGE_INTESTINE	Cellular response to environmental stimulus →	+0.049	+2.529	<.001	<.001	3	10
OESOPHAGUS	Protein localization to cell surface →	+0.153	+1.995	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,718 associations by consensus.

Protein activation cascade by ZNF185 expression — PANCREAS

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