ZNF184

Across TCGA patient cohorts, ZNF184 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF184-associated genes across cancer lineages are INPP4B, ATM, and Cyclin-B1. Each is linked with ZNF184 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF184-to-partner and partner-to-ZNF184 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by ZNF184-low versus ZNF184-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF184→partner) and Y-score (partner→ZNF184) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.471	-3.000	.014	.035	3	2
COAD	ATM →	-0.556	-2.991	.005	.036	3	2
UCEC	Cyclin-B1 →	+0.710	+1.999	<.001	<.001	3	2
UCEC	A-Raf_pS299 →	-0.097	-1.125	.006	.033	3	2
UCEC	FASN →	+0.281	+1.530	.018	.004	3	2
UCEC	JNK_pT183_Y185 →	-0.146	-1.517	.004	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

INPP4B by ZNF184 expression — COAD

Explore this box plot interactively →