ZNF184

Across TCGA cell cohorts, ZNF184 mutation is significantly associated with the drug of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF184-associated genes across cancer lineages are AZD1208, ULK1_4989, and WIKI4. Each is linked with ZNF184 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF184-to-partner and partner-to-ZNF184 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AZD1208 grouped by ZNF184-low versus ZNF184-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF184→partner) and Y-score (partner→ZNF184) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AZD1208 →	+0.352	+2.064	.019	.035	3	1
LARGE_INTESTINE	ULK1_4989 →	+0.573	+2.064	.047	.035	3	1
LARGE_INTESTINE	WIKI4 →	+0.331	+2.825	.018	.023	3	1
LARGE_INTESTINE	AKT inhibitor VIII →	+0.468	+2.067	.038	.033	3	1
LARGE_INTESTINE	Idelalisib →	+0.363	+2.807	.034	.032	3	1
LARGE_INTESTINE	WZ3105 →	+0.663	+2.067	.028	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

AZD1208 by ZNF184 expression — LARGE_INTESTINE

Explore this box plot interactively →