ZNF18

Across TCGA patient cohorts, ZNF18 protein abundance is significantly associated with the protein abundance of many other proteins, with 665 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF18-associated proteins across cancer lineages are AVEN_S261, BICRA_T921, and ABAT. Each is linked with ZNF18 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF18-to-partner and partner-to-ZNF18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF18 versus AVEN_S261 in PDAC, with a Pearson correlation of -0.62.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF18→partner) and Y-score (partner→ZNF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	AVEN_S261 →	-0.778	-0.543	<.001	<.001	3	1
PDAC	BICRA_T921 →	+0.425	+0.507	<.001	<.001	3	1
PDAC	ABAT →	+1.077	+0.657	<.001	<.001	3	1
PDAC	BRD4_S1117 →	-0.514	-0.353	<.001	.003	3	1
PDAC	C1orf52_S158 →	+0.495	+0.325	.001	.007	3	1
PDAC	C2CD2L_T417 →	-0.847	-0.698	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 665 associations by consensus.

ZNF18 vs AVEN_S261 — PDAC

Explore this scatter interactively →