ZNF18

Across TCGA patient cohorts, ZNF18 mutation is significantly associated with the RNA expression of many other genes, with 2,651 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF18-associated genes across cancer lineages are RNU6-552P, BNIP3P16, and TRAJ42. Each is linked with ZNF18 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF18-to-partner and partner-to-ZNF18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-552P grouped by ZNF18-low versus ZNF18-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF18→partner) and Y-score (partner→ZNF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-552P →	+0.243	+4.481	.007	.009	3	2
UCEC	BNIP3P16 →	+0.378	+2.042	.003	.002	3	2
UCEC	TRAJ42 →	+0.538	+1.606	<.001	.005	3	2
UCEC	SNORD90 →	+0.238	+1.933	<.001	.002	3	2
UCEC	TDGF1P1 →	+0.050	+2.219	.005	.005	3	2
LIHC	RNU7-4P →	+0.573	+5.355	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,651 associations by consensus.

RNU6-552P by ZNF18 expression — LUAD

Explore this box plot interactively →