ZNF175

Across TCGA patient cohorts, ZNF175 mutation is significantly associated with the RNA expression of many other genes, with 1,716 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF175-associated genes across cancer lineages are RNU6-1195P, RPL7AP23, and SNRPGP1. Each is linked with ZNF175 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF175-to-partner and partner-to-ZNF175 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1195P grouped by ZNF175-low versus ZNF175-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF175→partner) and Y-score (partner→ZNF175) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-1195P →	+0.219	+4.433	<.001	.007	3	2
PAAD	RPL7AP23 →	+0.056	+6.849	<.001	<.001	3	2
PAAD	SNRPGP1 →	+0.193	+5.053	<.001	.008	3	2
PAAD	MIR4769 →	+0.580	+5.824	<.001	.002	3	2
SKCM	IL9 →	+0.159	+3.452	<.001	.001	3	2
CESC	OR2U1P →	+0.070	+6.927	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,716 associations by consensus.

RNU6-1195P by ZNF175 expression — BLCA

Explore this box plot interactively →