ZNF175

Across TCGA cell cohorts, ZNF175 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,248 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF175-associated GO terms across cancer lineages are Retrograde transport, endosome to Golgi, Regulation of hippo signaling, and mRNA splice site recognition. Each is linked with ZNF175 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZNF175-to-partner and partner-to-ZNF175 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde transport, endosome to Golgi grouped by ZNF175-low versus ZNF175-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF175→partner) and Y-score (partner→ZNF175) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Retrograde transport, endosome to Golgi →	+0.056	+0.710	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Regulation of hippo signaling →	+0.072	+0.866	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.156	+0.902	<.001	<.001	3	11
SKIN	Endosomal transport →	+0.048	+0.877	.004	.001	2	12
SKIN	Cytosolic transport →	+0.057	+0.756	.001	.005	3	11
BLOOD_Lymphoma	Negative regulation of mRNA splicing, via spliceosome →	+0.103	+0.903	<.001	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,248 associations by consensus.

Retrograde transport, endosome to Golgi by ZNF175 expression — SKIN

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