ZNF175

Across TCGA cell cohorts, ZNF175 mutation is significantly associated with the drug of many other genes, with 34 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF175-associated genes across cancer lineages are PD0325901, GSK2801, and WYE-125132. Each is linked with ZNF175 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF175-to-partner and partner-to-ZNF175 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PD0325901 grouped by ZNF175-low versus ZNF175-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF175→partner) and Y-score (partner→ZNF175) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PD0325901 →	-0.564	-2.745	.025	.047	3	1
LARGE_INTESTINE	GSK2801 →	+0.297	+2.871	.049	.021	3	1
LARGE_INTESTINE	WYE-125132 →	+0.713	+2.874	.002	.021	3	1
LARGE_INTESTINE	CI-1033 →	+0.792	+2.874	.004	.021	3	1
LARGE_INTESTINE	RU-SKI 43 →	+0.336	+2.807	.048	.044	3	1
LARGE_INTESTINE	UNC0642 →	+0.217	+2.658	.020	.043	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

PD0325901 by ZNF175 expression — LARGE_INTESTINE

Explore this box plot interactively →