ZNF174

Across TCGA patient cohorts, ZNF174 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,203 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF174-associated proteins across cancer lineages are THUMPD1, USP7, and RPS6. Each is linked with ZNF174 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF174-to-partner and partner-to-ZNF174 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF174 versus THUMPD1 in OV, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF174→partner) and Y-score (partner→ZNF174) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	THUMPD1 →	+0.443	+0.369	<.001	.005	3	7
LSCC	USP7 →	+0.203	+0.537	<.001	<.001	3	6
BRCA	RPS6 →	-0.426	-0.564	.001	<.001	2	7
GBM	S100A12 →	-1.110	-0.231	<.001	<.001	3	6
HNSC	GTF3C4 →	+0.352	+0.626	<.001	<.001	3	6
BRCA	HIRIP3_S300 →	+0.842	+0.419	.007	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,203 associations by consensus.

ZNF174 vs THUMPD1 — OV

Explore this scatter interactively →