ZNF174

Across TCGA cell cohorts, ZNF174 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF174-associated genes across cancer lineages are TNP1 and ELOA3DP. Each is linked with ZNF174 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF174-to-partner and partner-to-ZNF174 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNP1 grouped by ZNF174-low versus ZNF174-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF174→partner) and Y-score (partner→ZNF174) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNP1 →	+0.128	+4.415	<.001	.007	3	1
LARGE_INTESTINE	ELOA3DP →	+0.044	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TNP1 by ZNF174 expression — LARGE_INTESTINE

Explore this box plot interactively →