Across TCGA patient cohorts, ZNF17 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF17-associated genes across cancer lineages are Notch1, Annexin-1, and TAZ. Each is linked with ZNF17 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF17-to-partner and partner-to-ZNF17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF17→partner) and Y-score (partner→ZNF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.174	+2.128	<.001	.009	3	2
SKCM	Annexin-1 →	+0.560	+3.169	.025	.019	2	2
SKCM	TAZ →	+0.316	+2.820	<.001	.035	3	1
UCEC	Gab2 →	+0.241	+1.247	.047	.045	3	1
UCEC	Ku80 →	+0.159	+1.261	.048	.029	3	1
UCEC	MEK1 →	+0.274	+2.321	.027	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

ZNF17 survival (RNA) · tumor vs normal (RNA) · all ZNF17 data types