ZNF17

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF17 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF17-associated genes across cancer lineages are OR52L1, OC90, and TLE7. Each is linked with ZNF17 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF17-to-partner and partner-to-ZNF17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF17→partner) and Y-score (partner→ZNF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSOR52L1 →+0.170+4.017<.001.00731
BLOOD_LeukemiaOC90 →+0.013+5.201<.001.00631
BLOOD_LeukemiaTLE7 →+0.022+5.969<.001.00131
LARGE_INTESTINEMROH5 →+0.073+2.882.001.00531
LARGE_INTESTINEPATE4 →+0.024+3.247.001.00131
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

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