ZNF160

Across TCGA patient cohorts, ZNF160 mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF160-associated genes across cancer lineages are p62 Lck ligand, eEF2, and MEK1. Each is linked with ZNF160 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF160-to-partner and partner-to-ZNF160 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by ZNF160-low versus ZNF160-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF160→partner) and Y-score (partner→ZNF160) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.347	+2.097	.001	.003	3	3
UCEC	eEF2 →	+0.347	+1.321	.003	.029	3	2
UCEC	MEK1 →	+0.497	+3.906	<.001	<.001	3	2
UCEC	Notch1 →	+0.147	+1.874	.001	.002	3	2
UCEC	Smad3 →	+0.134	+2.000	.007	.009	3	2
SKCM	Snail →	-0.194	-2.987	.014	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

p62 Lck ligand by ZNF160 expression — UCEC

Explore this box plot interactively →