ZNF160

Across TCGA cell cohorts, ZNF160 mutation is significantly associated with the RNA expression of many other genes, with 126 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF160-associated genes across cancer lineages are DNAAF6, IL22, and OR2D3. Each is linked with ZNF160 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF160-to-partner and partner-to-ZNF160 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAAF6 grouped by ZNF160-low versus ZNF160-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF160→partner) and Y-score (partner→ZNF160) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	DNAAF6 →	+0.021	+4.472	.001	.004	3	2
URINARY_TRACT	IL22 →	+0.017	+4.087	<.001	.009	3	1
URINARY_TRACT	OR2D3 →	+0.015	+4.087	<.001	.009	3	1
URINARY_TRACT	RNASE9 →	+0.012	+4.087	<.001	.009	3	1
SKIN	CRYGD →	+0.570	+6.000	<.001	<.001	3	1
LUNG_NSCLC_LUAD	URAD →	+0.054	+4.371	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 126 associations by consensus.

DNAAF6 by ZNF160 expression — CNS

Explore this box plot interactively →