ZNF16

Across TCGA patient cohorts, ZNF16 protein abundance is significantly associated with the RNA expression of many other genes, with 418 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF16-associated genes across cancer lineages are NCF4, POLE2, and VCPKMT. Each is linked with ZNF16 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF16-to-partner and partner-to-ZNF16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF16 versus NCF4 in LSCC, with a Pearson correlation of -0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF16→partner) and Y-score (partner→ZNF16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NCF4 →	-0.841	-0.519	.006	.001	3	1
LSCC	POLE2 →	+0.955	+0.475	.001	.001	3	1
LSCC	VCPKMT →	+0.717	+0.674	.002	<.001	3	1
LSCC	PIGH →	+0.589	+0.532	<.001	<.001	3	1
LSCC	AHSA1 →	+0.651	+0.440	.003	.008	3	1
LSCC	DAAM1 →	+0.635	+0.569	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 418 associations by consensus.

ZNF16 vs NCF4 — LSCC

Explore this scatter interactively →