ZNF16

Across TCGA cell cohorts, ZNF16 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,250 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZNF16-associated GO terms across cancer lineages are Positive regulation of stem cell population maintenance, Central nervous system morphogenesis, and Blastocyst growth. Each is linked with ZNF16 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF16-to-partner and partner-to-ZNF16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stem cell population maintenance grouped by ZNF16-low versus ZNF16-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF16→partner) and Y-score (partner→ZNF16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of stem cell population maintenance →	+0.069	+0.448	<.001	<.001	3	11
LIVER	Central nervous system morphogenesis →	-0.279	-0.808	<.001	.001	3	10
LARGE_INTESTINE	Blastocyst growth →	+0.118	+0.392	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of double-strand break repair →	+0.078	+0.758	.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Establishment of mitotic sister chromatid cohesion →	+0.087	+0.548	.007	.002	3	8
BONE	Cellular response to salt →	+0.134	+0.757	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,250 associations by consensus.

Positive regulation of stem cell population maintenance by ZNF16 expression — LUNG_SCLC

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