ZNF16

Across TCGA cell cohorts, ZNF16 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF16-associated genes across cancer lineages are C1QC, VSX2, and GTF2A1L. Each is linked with ZNF16 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF16-to-partner and partner-to-ZNF16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1QC grouped by ZNF16-low versus ZNF16-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF16→partner) and Y-score (partner→ZNF16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	C1QC →	+0.023	+4.432	<.001	.003	3	1
BLOOD_Leukemia	VSX2 →	+0.021	+3.744	.004	.003	3	1
BLOOD_Leukemia	GTF2A1L →	+0.094	+3.534	.003	.005	3	1
LUNG_NSCLC_LUAD	PDE6H →	+0.085	+3.951	.007	.005	3	1
LUNG_NSCLC_LUAD	TBATA →	+0.184	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	FAM47A →	+0.051	+3.734	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

C1QC by ZNF16 expression — STOMACH

Explore this box plot interactively →