ZNF157

Across TCGA patient cohorts, ZNF157 mutation is significantly associated with the RNA expression of many other genes, with 4,897 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF157-associated genes across cancer lineages are TRDJ2, AQP7P4, and TRAJ39. Each is linked with ZNF157 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF157-to-partner and partner-to-ZNF157 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRDJ2 grouped by ZNF157-low versus ZNF157-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF157→partner) and Y-score (partner→ZNF157) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TRDJ2 →	+0.813	+3.234	.001	.009	3	3
CESC	AQP7P4 →	+0.057	+4.539	<.001	.001	3	2
CESC	TRAJ39 →	+0.625	+3.797	.008	.005	3	2
LGG	PTP4A1P5 →	+0.064	+7.977	<.001	.007	3	2
LGG	MIR548H5 →	+0.381	+7.977	<.001	.007	3	2
CESC	CDC27P1 →	+0.045	+3.612	.006	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,897 associations by consensus.

TRDJ2 by ZNF157 expression — CESC

Explore this box plot interactively →