ZNF157

Across TCGA cell cohorts, ZNF157 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF157-associated genes across cancer lineages are OR2T1, SELE, and OC90. Each is linked with ZNF157 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF157-to-partner and partner-to-ZNF157 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2T1 grouped by ZNF157-low versus ZNF157-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF157→partner) and Y-score (partner→ZNF157) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR2T1 →	+0.020	+5.247	<.001	.001	3	1
BLOOD_Lymphoma	SELE →	+0.050	+4.350	<.001	.005	3	1
LUNG_NSCLC_LUAD	OC90 →	+0.013	+4.371	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR2T1 by ZNF157 expression — BLOOD_Lymphoma

Explore this box plot interactively →