Across TCGA patient cohorts, ZNF155 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF155-associated genes across cancer lineages are 4E-BP1, EGFR_pY1068, and eIF4E. Each is linked with ZNF155 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF155-to-partner and partner-to-ZNF155 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF155→partner) and Y-score (partner→ZNF155) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.237	+1.678	.022	.023	3	2
UCEC	EGFR_pY1068 →	-0.298	-3.807	.001	<.001	3	1
UCEC	eIF4E →	+0.230	+3.700	.004	.001	3	1
UCEC	A-Raf_pS299 →	-0.126	-2.000	.006	.030	3	1
UCEC	ERK2 →	+0.152	+3.169	.040	.018	3	1
UCEC	JNK2 →	+0.226	+1.678	.003	.023	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

ZNF155 survival (RNA) · tumor vs normal (RNA) · all ZNF155 data types