ZNF154

Across TCGA cell cohorts, ZNF154 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,479 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF154-associated GO terms across cancer lineages are Late viral transcription, Post-transcriptional gene silencing, and mRNA splice site recognition. Each is linked with ZNF154 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF154-to-partner and partner-to-ZNF154 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Late viral transcription grouped by ZNF154-low versus ZNF154-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF154→partner) and Y-score (partner→ZNF154) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Late viral transcription →	+0.175	+0.216	<.001	<.001	3	10
URINARY_TRACT	Post-transcriptional gene silencing →	+0.089	+0.280	<.001	.002	3	10
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.156	+0.153	<.001	<.001	3	10
BLOOD_Lymphoma	Constitutive heterochromatin formation →	+0.085	+0.505	<.001	.009	3	9
UPPER_AERODIGESTIVE_TRACT	Heterochromatin formation →	+0.053	+0.162	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of RNA splicing →	+0.074	+0.155	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,479 associations by consensus.

Late viral transcription by ZNF154 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →