ZNF154

Across TCGA cell cohorts, ZNF154 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF154-associated genes across cancer lineages are PTH and TPD52L3. Each is linked with ZNF154 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF154-to-partner and partner-to-ZNF154 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTH grouped by ZNF154-low versus ZNF154-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF154→partner) and Y-score (partner→ZNF154) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PTH →	+0.049	+3.684	<.001	.006	3	1
LARGE_INTESTINE	TPD52L3 →	+0.044	+3.684	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PTH by ZNF154 expression — LARGE_INTESTINE

Explore this box plot interactively →