ZNF146

Across TCGA patient cohorts, ZNF146 protein abundance is significantly associated with the RNA expression of many other genes, with 10,618 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF146-associated genes across cancer lineages are TMEM97, UBA2, and PM20D2. Each is linked with ZNF146 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF146-to-partner and partner-to-ZNF146 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF146 versus TMEM97 in HNSC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF146→partner) and Y-score (partner→ZNF146) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TMEM97 →	+0.993	+0.570	<.001	<.001	3	6
HNSC	UBA2 →	+0.710	+0.615	.001	.003	3	6
HNSC	PM20D2 →	+1.049	+0.888	.001	<.001	3	6
BRCA	LIN9 →	+0.858	+0.409	<.001	.001	3	6
HNSC	ZNF567 →	+0.934	+0.794	.006	.001	3	6
LSCC	RAD54B →	+0.640	+0.438	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,618 associations by consensus.

ZNF146 vs TMEM97 — HNSC

Explore this scatter interactively →