ZNF146

Across TCGA cell cohorts, ZNF146 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,156 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF146-associated GO terms across cancer lineages are Nuclear pore complex assembly, Nuclear pore organization, and Monoubiquitinated protein deubiquitination. Each is linked with ZNF146 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF146-to-partner and partner-to-ZNF146 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore complex assembly grouped by ZNF146-low versus ZNF146-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF146→partner) and Y-score (partner→ZNF146) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Nuclear pore complex assembly →	+0.105	+0.674	<.001	<.001	3	16
BREAST	Nuclear pore organization →	+0.124	+0.958	<.001	<.001	3	15
SOFT_TISSUE	Monoubiquitinated protein deubiquitination →	+0.131	+0.878	<.001	<.001	3	15
BREAST	Regulation of RNA export from nucleus →	+0.130	+0.894	<.001	<.001	3	15
BLOOD_Lymphoma	Regulation of DNA repair →	+0.050	+0.952	<.001	.001	3	14
KIDNEY	Sex-chromosome dosage compensation →	+0.124	+0.666	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,156 associations by consensus.

Nuclear pore complex assembly by ZNF146 expression — BREAST

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