ZNF143

Across TCGA cell cohorts, ZNF143 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,074 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF143-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Regulation of chromosome condensation, and DNA-templated DNA replication. Each is linked with ZNF143 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF143-to-partner and partner-to-ZNF143 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by ZNF143-low versus ZNF143-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF143→partner) and Y-score (partner→ZNF143) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Epigenetic regulation of gene expression →	+0.050	+0.445	<.001	<.001	3	14
BLOOD_Lymphoma	Regulation of chromosome condensation →	+0.183	+0.639	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.121	+0.796	<.001	<.001	3	14
BREAST	Centrosome cycle →	+0.084	+0.574	<.001	<.001	3	13
SOFT_TISSUE	Centrosome duplication →	+0.087	+0.516	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.099	+0.706	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,074 associations by consensus.

Epigenetic regulation of gene expression by ZNF143 expression — SOFT_TISSUE

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