Across TCGA patient cohorts, ZNF140 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF140-associated genes across cancer lineages are ACC1, IGFBP2, and NF-kB-p65_pS536. Each is linked with ZNF140 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF140-to-partner and partner-to-ZNF140 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF140→partner) and Y-score (partner→ZNF140) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.342	+2.013	.012	.016	3	1
UCEC	IGFBP2 →	-0.722	-1.765	.003	.014	3	1
UCEC	NF-kB-p65_pS536 →	-0.373	-2.999	.028	.035	3	1
UCEC	p27_pT157 →	-0.044	-1.960	.043	.030	3	1
UCEC	p90 RSK →	+0.188	+2.232	.008	.005	3	1
UCEC	PCNA →	+0.248	+3.584	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

ZNF140 survival (RNA) · tumor vs normal (RNA) · all ZNF140 data types