zinc finger protein 137, pseudogeneGenealiases: ZNF137 · pHZ-30
Q-omics provides the consensus-scored ZNF137P profile across patient tissues and cancer cell-line models. ZNF137P expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in LUSC. Among the 18 cancer types available for tumor–normal comparison, ZNF137P is differentially expressed in 8, with the highest sampling consensus in THCA. Additionally, ZNF137P RNA expression shows 21,311 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight LUSC, THCA, and THYM as cancer lineages where ZNF137P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ZNF137P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ZNF137P survival associations across molecular data types. ZNF137P RNA expression shows survival associations in the most cancer types (22), followed by mass-spec protein abundance (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ZNF137P RNA expression–survival associations across cancer types. High ZNF137P expression shows unfavorable associations in LUSC, LGG and COAD, but favorable associations in HNSC, UCS and THYM. The LUSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify LUSC as the clearest survival context for ZNF137P RNA expression.
This table summarizes ZNF137P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8, while mass-spec protein shows differences in 4. The strongest signals are observed in THCA for RNA and HNSC for protein.
This table ranks reproducible tumor–normal expression differences for ZNF137P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ZNF137P shows lower tumor expression in THCA and KICH and higher tumor expression in CHOL, LIHC, STAD and ESCA. The THCA box plot shows higher ZNF137P RNA expression in normal versus tumor tissue (log2 FC = −0.944, t-test p < 0.001).
This table shows molecular features associated with ZNF137P in patient tissues and cancer cell lines. In patient samples, ZNF137P shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, ZNF137P RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LUNG_NSCLC_LUAD, while CRISPR and shRNA rows add functional-dependency signals in STOMACH.
