Across TCGA patient cohorts, ZNF134 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF134-associated genes across cancer lineages are A-Raf_pS299, Ku80, and Notch1. Each is linked with ZNF134 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF134-to-partner and partner-to-ZNF134 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF134→partner) and Y-score (partner→ZNF134) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.101	-2.321	.040	.033	3	1
UCEC	Ku80 →	+0.255	+1.820	.008	.016	3	1
UCEC	Notch1 →	+0.142	+3.179	.014	.010	3	1
UCEC	p62 Lck ligand →	+0.295	+3.169	.028	.018	3	1
UCEC	PCNA →	+0.214	+2.321	.016	.006	3	1
UCEC	S6_pS240_S244 →	+0.370	+3.321	.027	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

ZNF134 survival (RNA) · tumor vs normal (RNA) · all ZNF134 data types