ZNF133

Across TCGA pan-cancer cohorts, ZNF133 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF133 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher ZNF133 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF133 expression acts as an unfavorable survival marker.

OV, COAD, and KICH are the cancer types where ZNF133 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Median	All	0.179	0.543	<.001	18	view →
COAD	OS	Median	All	0.140	0.874	<.001	15	view →
KICH	DFS	Median	All	0.102	0.848	.004	13	view →
BLCA	DFS	Median	IV	0.191	0.481	.035	6	view →
LUAD	OS	Median	All	0.523	0.836	.011	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZNF133–OV (DFS)

Open the OV breakdown →