ZNF133-AS1

Across TCGA pan-cancer cohorts, ZNF133-AS1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated ZNF133-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ZNF133-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF133-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and ACC show a favorable association.

KIRC, DLBC, and COAD are the cancer types where ZNF133-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	II,III,IV	0.279	0.589	.003	71	view →
DLBC	OS	Quartile	II,III,IV	0.618	0.942	.002	53	view →
COAD	DFS	Quartile	II,III,IV	0.622	0.802	.003	35	view →
KIRP	OS	Quartile	All	0.892	0.982	.007	35	view →
LIHC	OS	Tertile	All	0.689	0.807	.002	35	view →
BRCA	DFS	Quartile	All	0.971	0.934	.007	30	view →
HNSC	DFS	Median	IV	0.301	0.554	.006	30	view →
ACC	DFS	Median	All	0.833	0.633	.014	26	view →
PRAD	OS	Quartile	All	0.938	0.994	.007	16	view →
OV	OS	Median	All	0.813	0.866	.027	14	view →
THYM	OS	Quartile	All	0.770	1.000	.015	12	view →
UCS	DFS	Median	IV	0.952	0.367	.001	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

ZNF133-AS1–KIRC (DFS)

Open the KIRC breakdown →